Autistic adults face a profound mental health crisis, with significantly elevated rates of anxiety, depression, and loneliness. Yet systems of care, clinical services, and everyday environments are rarely designed with Autistic people in mind. Too often, diagnosis comes late, post-diagnostic support is minimal, and services fail to recognise the nuanced realities of Autistic lives. This keynote draws on the six priorities for change proposed by Mandy (2022)—from early identification and inclusive environments to adapted mental health pathways and autism-specific research—and explores what it looks like to translate these into practice. Grounded in participatory research and co-produced with Autistic adults, I will share emerging insights from a series of projects led by Aspect (Autism Spectrum Australia). These include the ‘Welcome Pack’, a freely available, self-guided resource that fosters identity, belonging, and self-compassion during a time of transition; research into airport accessibility that reveals how public environments can amplify distress or support dignity; a newly adapted measure of loneliness (UCLA-m) that better captures Autistic experience; and the ASPAA self-compassion program, which offers paced, affirming support for emotion regulation and wellbeing. Together, these studies challenge the notion that Autistic mental health struggles are addressed by focusing solely on the individual. Instead, they highlight the importance of considering the fit between Autistic people and broader social and structural systems. They also demonstrate how affirming tools, inclusive design, and co-created supports can help build connection and contribute to improved wellbeing.